地址:武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301
电话:15172469628
传真:15172469628
邮箱:sales@amyjet.com

Allele Biotechnology位于美国圣地亚哥市,主要专注于对生物过程的机制进行探索,以开发生物医学及治疗相关的技术和产品。以各个物种的iPS细胞、人类cGMP iPS细胞及衍生的细胞为材料,Allele Biotechnology利用专利性的非整合细胞编辑方法,开发了出了细胞治疗和药物筛选的技术。Allele Biotechnology具有深厚的基因组修饰和细胞荧光报告因子的经验,为客户提供优异的细胞检测解决方案。Allele Biotechnology还提供荧光蛋白、高效荧光素酶底物、基因分型试剂盒、骆驼抗体等产品;此外还在RNA干扰领域尤其独特的专利。
Allele Biotechnology and Pharmaceuticals, Inc. is a private, San Diego-based company that explores the mechanisms of biological processes to develop technologies and products for biomedical research and therapy development.
Our mission is to increase accessibility to innovative molecular biology research tools by offering cutting edge technologies in individual products and fully integrated platforms. Allele utilizes proprietary non-integrating cellular reprogramming methods to develop cell therapy and enable drug discovery through the use of human and non-human primate iPS cells, cGMP-grade human iPS cells and their derivatives. With additional expertise in genome modification and unique cell-based fluorescence sensors/reporters, Allele provides advanced cell and assay development solutions. Allele also has developed a wide variety of advanced research tools including superior fluorescent proteins, highly efficient luciferase assay substrates, genotyping kits, and camelid antibodies that have been validated for co-immunoprecipitation, histology, and flow cytometry. The Company has also been a leader in the RNAi field with its patents in Pol III promoter-driven siRNA, shRNA, and miRNA.
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OncoImmunin products are continually expanding in response to the needs of the biomedical community, whether engaged in basic or developmental research. Many of OncoImmunin’s probes are a direct result of interactions between OncoImmunin scientists and the research community.
OncoImmunin的主要产品包括:
Patented Technologies
Apoptosis
Drug Delivery
Licensing and Screening
Cancer Metastasis
Cellular Cytotoxicity
Inflammation
Information
Viral Detection
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艾美捷科技有限公司
全国服务热线:400-6800-868
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网站:www.amyjet.com
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艾美捷科技代理Dovetail Genomics品牌全系列产品
Dovetail Genomics公司成立于2013年,是染色体级别基因组组装领域的创新者,Dovetail Genomics公司正在解决包括染色质拓扑结构分析、大小体细胞变异检测、从头染色体组装和单倍型定相在内的复杂问题。Dovetail Genomics通过其专利的Hi-C/Omini-C技术,填补了短读长测序无法完成高质量组装的空白,产品广泛应用于表观遗传学、发育生物学、癌症研究、进化生物学、传染病等领域。

▍Dovetail Genomics公司的产品
| Dovetail Assay | ||||||
| Application | LinkPrep™ | Micro-C | HiChIP | Pan Promoter | Omni-C | |
| Genetic Variation | Large Structural Variant Detection Genotyping | √ | ||||
| Genotyping | √ | |||||
| Haplotype Phasing | √ | √ | ||||
| Chromatin Topology | Targeted Enhancer- Promoter Interactions | |||||
| Nucleosome-level Chromatin Topology | √ | |||||
| Whole Genome Rapid High-Resolution Topology | √ | |||||
| Protein Anchored Topology | √ | |||||
| Genetic Genome Assembly | Genome Scaffolding | √ | √ | |||
| Hybrid Capture Compatible | √ | √ | √ | |||
▍Dovetail® LinkPrep™ Kit
采用Tn5转座酶实现染色质均匀片段化,确保捕获无偏差的完整染色质三维构象。产品特点:
● 单日工作流:样本→测序文库仅需8小时(传统Hi-C需3-5天)
● 零专用设备:兼容常规分子生物学实验室
● 实现单倍型定相组装(Haplotype-resolved)
● 同步捕获全谱变异:SNV/InDel/CNV/SV(灵敏度达95%)
● 适用于基因组拓扑结构、遗传变异、基因组组装
▍Dovetail® Micro-C Kit
获取核小体分辨率的三维基因组图谱,针对需要单核小体级别精细拓扑图谱的研究(解析150-200 bp染色质构象),本技术可逐层解锁基因组三维结构。其在1千碱基对(kbp)以下分辨率呈现的高信噪比特性,使研究者能够以显著降低的成本构建高质量的染色质互作矩阵。产品特点:
● 核小体级精度:直接解析 150-200 bp染色质基本单元(单核小体)的空间构象,突破传统Hi-C技术分辨率限制(通常>1 kbp)
● 超高信噪比优势:在亚千碱基级别消除背景噪音,精确捕获微尺度拓扑关联域(如增强子-启动子互作)
● 成本降低:相较冷冻电镜或ChIA-PET等方法,实验成本下降60-80%; 矩阵数据质量提升(矩阵信噪比 > 95%,传统方法约70-85%)
▍Dovetail® Pan Promoter Kit
专为绘制“基因启动子-调控元件”三维互作图谱设计,通过靶向富集技术实现高分辨率、低成本的染色质构象分析。
▍Dovetail® HiChIP Kit
抗体导向的精准三维基因组捕获系统,融合Hi-C空间架构捕获与ChIP靶向富集技术,实现对特定蛋白(如CTCF、Cohesin、组蛋白修饰)介导的染色质互作进行纳米级分辨率解析。产品特点:
● 分辨率:200 bp(单核小体水平)
● 灵敏度:检测低频互作(≥5个细胞中1次事件)
● 特异性:抗体结合位点富集度 >100X;非特异性背景 <2%
● 样本兼容性:冰冻组织、FFPE样本、单细胞悬液
▍Dovetail® Omni-C® Kit
通过Tn5转座酶同时捕获染色质空间互作与酶切位点信息,核心优势:
● 高分辨率:精准解析拓扑关联结构域(TADs)、染色质环
● 多组学整合:单次实验同步检测染色质构象+基因变异(SNV/InDel/CNV/SV)
● 样本兼容性:支持微量样本(>50mg组织/ >10,000个细胞)
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地址:武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301
电话:18995651644
传真:18372041646
邮箱:sales@amyjet.com
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